you can use it for the protection circuit. But input signal logic level should also be between 4-5 volt. It may be from a microcontroller or any other device.
LIN pin 12 is an input signal for low side Mosfet driver output. But input signal logic level should be between 4-5 volt. 
HIN pin 10 is an input signal for high side MOSFET driver output. But if you used voltage less than 4 volts it may not give you the required result. When hen input to low side at pin 12 Lin is low, LO output will be equal to the value of VSS and it means zero. Because when an input to the low side at pin 12 Lin is high, LO output will be equal to the value of Vcc voltage at pin 3 with respect to Vss and COM pin. It is at the same potential as ground VSS pin 13. pin2 is a return path for the low side. Pin 1 is the output of low side MOSFET drive. This figure represents the pin diagram of IR2210 MOSFET driver IC. IR2110 floating circuit can drive high side MOSFET up to 500 volts. Its output pins can provide peak current up to 2 amperes. IR2210 can withstand voltage up to 500v (offset voltage). It has a floating circuit to handle to bootstrap operation. International rectifiers IR2110 MOSFET driver can be used as a high side and low side MOSFET driver. In H bridge used in pure sine wave inverter design 2 MOSFET are used as high side MOSFET and 2 MOSFET is used as low side MOSFET. In many applications, a floating circuit is required to drive high side MOSFET. high side and low side MOSFET driver in half-bridge. 
IR2110 as low side or high side MOSFET DRIVER. If peak current required for your application is too high to handle for MOSFET driver IC, you can use external totem-pole output or complementary MOSFET circuits. NOTE: the current required to drive a MOSFET gate is very low but peak current somehow greater than average current. 
To know about totem pole output and its used a Mosfet driver go through the following article: Because it has low input impedance and high drive current. But almost all MOSFET drivers used totem pole output. There are many types of MOSFET drivers available in the market. MOSFET drivers are used to avoiding these issues. This problem is known as the miller effect. High voltage on the drain of MOSFET cause problem by interaction with gate-drain capacitance. One can do it very easily but there is one issue. Why we need a MOSFET driver? Because MOSFETs are voltage control devices and used to drive MOSFET the gate capacitance should be charged to operating voltage which is usually between 9-10 volt. How to use a MOSFET driver? MOSFET driver circuits are used to drive MOSFETS in a high side or low side. It can drive both low side and high side switches in half-bridge and low bridge circuits. IR2110 is a high voltage MOSFET driver IC.
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